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Yeungnam Univ J Med > Volume 26(2); 2009 > Article
Yeungnam University Journal of Medicine 2009;26(2):93-101.
DOI: https://doi.org/10.12701/yujm.2009.26.2.93    Published online December 31, 2009.
Use of Magnesium in Anesthesiology and Pain Medicine.
Chae Rim Seong, Dae Lim Jee
Department of Anesthesiology and Pain Medicine, College of Medicine, Yeungnam University, Daegu, Korea. djee@medical.yeungnam.ac.kr
Abstract
The use of magnesium sulphate has recently increased in anesthesiology and pain medicine. The roles of magnesium sulphate are as an analgesic adjuvant, a vasodilator, a calcium channel blocker and reducing the anesthetic requirement. These effect are primarily based on the regulation of calcium influx into the cell and antagonism of the N-methyl-D-aspartate receptor. We discuss here the clinical effects of magnesium sulphate on anesthesiology and pain medicine.
Key Words: Magnesium sulphate, Calcium channel blocker, N-methyl-D-aspartate
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