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Yeungnam Univ J Med > Volume 29(2); 2012 > Article
Yeungnam University Journal of Medicine 2012;29(2):145-149.
DOI: https://doi.org/10.12701/yujm.2012.29.2.145    Published online December 31, 2012.
A Case of Chronic Renal Failure Associated with Systemic Capillary Leak Syndrome.
Seon Ha Baek, Nara Shin, Hyo Jin Kim, Mi Yeun Han, Dong Ju Choi, Soo Mee Bang, Sejoong Kim, Jin Ho Paik
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. imsejoong@daum.net
2Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
3Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
4Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
Abstract
Systemic capillary leak syndrome (SCLS) is an unusual entity characterized by hypovolemic shock, hemoconcentration, and hypo-albuminemia associated with paraproteinemia as a result of marked capillary hyperpermeability. Complications of this syndrome can include compartment syndromes, pulmonary edema, thrombosis, and acute kidney injury. This paper reports a case of severe SCLS accompanied by acute tubular necrosis caused by hypoperfusion and myoglobinuria secondary to rhabdomyolysis, which resulted in chronic kidney disease that necessitated hemodialysis. However, there have been rare data of residual end-organ damage after acute attacks in Korea. Therefore, this paper reports a case of complicated SCLS enough to hemodialysis and that developed into chronic kidney disease.
Key Words: Acute tubular necrosis, Rhabdomyolysis, Systemic capillary leak syndrome, Chronic renal failure


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