Yeungnam Univ J Med Search

CLOSE


Yeungnam Univ J Med > Volume 8(2); 1991 > Article
Yeungnam University Journal of Medicine 1991;8(2):63-69.
DOI: https://doi.org/10.12701/yujm.1991.8.2.63    Published online December 31, 1991.
Nucleolar organizer regions in glioma.
Hae Joo Nam, Dong Suk Kim, Won Hee Choi, Tae Sook Lee
Abstract
Nucleolar organizer regions (NOR) are loops of ribosomal DNA (rDNA) which are transcribed by RNA polymerase I. They produce ultimately ribosome and protein. Thus they are believed to reflect nuclear activity. We applied silver colloid staining technique to human glioma to examine relationship between the mean number of Ag-NOR and histopathological grading. The mean number of Ag-NOR (±S. E of the mean) were 1.17±0.07 in normal brain, 1.53±0.25 in astrocytoma, 2.37±0.71 in malignant astrocytoma. And 2.88±0.41 in glioblastoma multiforme. And there was a statistically significant difference among these. The results show that Ag-NOR technique is a rather simple and rapid method and will become a helpful tool for estimation of the proliferative potential of glioma.
Key Words: Glioma, Nucleolar organizer regions
TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 0 Crossref
  •    
  • 47 View
  • 0 Download
Related articles in Yeungnam Univ J Med


ABOUT
ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
170 Hyeonchung-ro, Nam-gu, Daegu 42415, Korea
Tel: +82-53-640-6832    Fax: +82-53-651-0394    E-mail: yujm@yu.ac.kr                

Copyright © 2019 by Yeungnam University College of Medicine. All rights reserved.

Developed in M2community

Close layer
prev next