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Yeungnam Univ J Med > Volume 10(2); 1993 > Article
Yeungnam University Journal of Medicine 1993;10(2):485-492.
DOI:    Published online December 31, 1993.
Histopathologic findings of necrotizing lymphadenitis.
Young Ran Shim, Hae Joo Nam
Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and Small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.


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