Journal of Yeungnam Medical Science

Acute left main coronary artery thrombosis as an initial presentation of systemic lupus erythematosus: Kang Un Choi, Ung Kim; Yeungnam Univ J Med. 2018;35(2):227-231. Published online December 31, 2018; DOI: https://doi.org/10.12701/yujm.2018.35.2.227

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Abstract PDF: Left main coronary artery (LMCA) thrombosis is rare and the cause should be determined. A previously healthy young man presented with severe chest pain and dyspnea. The electrocardiogram showed typical ST-segment elevation myocardial infarction with clinical instability. Emergency coronary angiography revealed complete LMCA occlusion by thrombosis. After reperfusion, the patient was admitted to the cardiac care unit. He was diagnosed with hemolytic anemia and tested positive for antinuclear antibodies. Systemic lupus erythematosus (SLE) and LMCA disease due to systemic thrombosis were diagnosed. Steroids were started and the patient was discharged without complications. We report this rare case of LMCA thrombosis as an initial presentation of SLE.

Budd-Chiari syndrome with antiphospholipid syndrome and systemic lupus erythematosus in a patient with Klinefelter's syndrome: Mingee Lee, Jin Young Huh, Ji Hyang Lee, Sun myoung Kang, Jae Yong Lee, Oh Chan Kwon, Eun Na Kim, Jihun Kim, Danbi Lee; Yeungnam Univ J Med. 2017;34(2):260-264. Published online December 31, 2017; DOI: https://doi.org/10.12701/yujm.2017.34.2.260

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Abstract PDF: Klinefelter's syndrome is the most common congenital abnormality that causes primary hypogonadism. It is associated with diseases that predominantly affect women, such as systemic lupus erythematosus (SLE), and it can sometimes cause veno-occlusive disease. We experienced a case of Budd-Chiari syndrome (BCS) in a 33-year-old man with Klinefelter's syndrome presented with hematemesis and edema in both lower extremities. The clinical and laboratory findings were compatible with SLE, antiphospholipid syndrome, and BCS. To the best of our knowledge, this is the first case report to describe a simultaneous presentation of these four clinical syndromes in a single patient.

Brain meningioma in a patient with systemic lupus erythematosus.: Byung Woo Yoo, Sung Soo Ahn, Jung Yoon Pyo, Se Jin Byun, Jason Jungsik Song, Yong Beom Park, Soo Kon Lee, Jung Soo Song, Sang Won Lee; Yeungnam Univ J Med. 2016;33(2):159-161. Published online December 31, 2016; DOI: https://doi.org/10.12701/yujm.2016.33.2.159

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Brain meningioma, the most common benign brain tumor, has been reported to account for 13-26% of all intracranial tumors, with a crude incidence rate of 2.3 per 100,000 persons for all types of meningiomas. The prevalence of neuropsychiatric lupus erythematosus is 15-91% and its clinical manifestations are diverse: from mild cognitive dysfunction to serious neurological or psychiatric symptoms. Here, we report the first Korean patient with brain meningioma and systemic lupus erythematosus who had undergone surgical tumor resection.

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High-grade spheno-orbital meningioma in patients with systemic lupus erythematosus: Two case reports and literature review
Sarah Bin Abdulqader, Nasser Almujaiwel, Wafa Alshakweer, Gmaan Alzhrani
Surgical Neurology International.2020; 11: 367. CrossRef

A Case of Systemic Lupus Erythematosus Misdiagnosed as Adult-onset Still's Disease.: Myung Jin Oh, Hyun Je Kim, Han Sol Lee, Ji An Hur, Young Hoon Hong, Choong Ki Lee; Yeungnam Univ J Med. 2010;27(1):78-84. Published online June 30, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.1.78

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Abstract PDF: Adult-onset Still's disease (AOSD) is an inflammatory disorder that's characterized by daily, spiking high fever, arthritis and an evanescent, salmon-pink rash. AOSD is diagnosed purely on the basis of the typical clinical features of the illness. The symptoms commonly include swelling of the lymph nodes, enlargement of the spleen and liver, and a sore throat. AOSD is difficult to differentiate from systemic lupus erythematosus (SLE) due to the similar clinical manifestations. We report here on a case of a 16-year-old female patient with autism and epilepsy and who complained of daily spiking fever for 20 days. The patient had maculopapular skin rashes on the face and whole body and lymphadenopathy. The liver function tests were elevated mildly. The initial rheumatoid factor (RF) and antinuclear antibody (ANA) tests were negative. We diagnosed her as having adult-onset Still's disease according to the criteria of Yamaguchi. We successfully treated her with oral prednisolone. But her antinuclear antibody test was changed to positive after discharge. So we finally diagnosed her as having SLE.

One Case of Lupus Nephritis Flare in Child During Tapering the Steroid: Jung Youn Choi, Yong Hoon Park; Yeungnam Univ J Med. 2007;24(2 Suppl):S755-760. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S755

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Abstract PDF: Systemic lupus erythematosus (SLE) is a chronic multisystemic inflammatory autoimmune disease. Hematologic abnormality is more frequent and the frequency of using high dose steroid and immunosuppressant as treatment is higher in children, because the number of involved major organ is numerous and the disease progress is often rapid in the SLE of children. We reported an experience of lupus nephritis flare after tapering the steroid in 9 years old boy who was diagnosed focal proliferative glomerulonephritis.

A Case of Systemic Lupus Erythematosus Presenting with Amaurosis Fugax without Antiphospholipid Antibodies Syndrome.: Jung Hyun Kim, Jung Sang Hah, Mee Young Park, Se Jin Lee, Jun Lee; Yeungnam Univ J Med. 2006;23(1):113-117. Published online June 30, 2006; DOI: https://doi.org/10.12701/yujm.2006.23.1.113

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Abstract PDF: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect many organ systems including the nervous system. The immune response in patients with SLE can cause inflammation and other damage that can cause significant injury to the arteries and tissues. A 48-year-old woman was admitted to the hospital because of transient monocular blindness. Magnetic resonance imaging and conventional angiography showed severe stenosis of the distal intracranial internal carotid artery. The patient was diagnosed as having SLE but the antiphospholipid antibodies were negative. Amaurosis fugax has not been previously reported as an initial manifestation of SLE in Korea. We report a patient with a retinal transient ischemic attack as the first manifestation of SLE.

A Case of Protein-losing Enteropathy Treated with High Dose Intravenous Glucocorticoid Therapy in Systemic Lupus Erythematosus.: Kyu Hyung Lee, Chang Mo Kwon, Hyun Do Kim, Dae Young Yun, Jae Yoong Lee, Yeong Hoon Hong, Choong Ki Lee; Yeungnam Univ J Med. 2005;22(2):253-258. Published online December 31, 2005; DOI: https://doi.org/10.12701/yujm.2005.22.2.253

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Generalized edema and hypoalbuminemia are relatively common presenting manifestations in many clinical situations. The differential diagnosis of hypoalbuminemia include: Kwashiorkor, synthetic dysfunction of the liver, and excessive protein loss as in nephrotic syndrome. In systemic lupus erythematosus (SLE), hypoalbuminemia and generalized edema are most commonly due to protein loss associated with lupus nephritis; gastrointestinal involvement is uncommon, and therefore protein loss through the gastrointestinal tract is quite rare. We report a case of a protein losing enteropathy (PLE) associated with SLE. The patient was referred to our hospital for generalized edema, arthralgia and facial rash. After clinical evaluation, the patient met the criteria for the SLE diagnosis; hypoalbuminemia with general edema was consistent with a protein losing enteropathy. After two weeks of therapy with parenteral high dose glucocorticoid, the patients was improved in laboratory findings as well as clinical symptoms.

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A Case of Protein Losing Enteropathy as Only Clinical manifestation of Systemic Lupus Erythematosus
Tae Hyun Kim, Yu Hee Choi, Lae Hyung Kang, Hyeong Jin Kim, Jin Ho Jang, Min Wook So
Kosin Medical Journal.2017; 32(1): 84. CrossRef

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